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Under federal law, compounded medications may be prepared by state-licensed pharmacies for individual patients whose needs cannot be met by approved products or, in limited circumstances, while a product is on the FDA's shortage listsubject to strict conditions under Section 503A and 503B of the Federal Food, Drug, and Cosmetic Act

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Polyethylene glycol (PEG) is a water-soluble inert polymer that reduces the renal clearance of the drug and prolongs the half-life, in addition to enhancing water solubility and preventing proteolysis

It is important to distinguish between a direct pharmacological effect and secondary consequences of treatment

Stress: Chronic stress disrupts sleep and increases cortisol levels, both of which are linked to fat storage